Posted on December 22, 2009.
The News of redglisse - the Secondary Effects, the Remedies of Usages and Takes advantage herbier
Classify taxinomique
Fabaceae
The common Commerce Names
Preparations of multi-ingreddient: Of of of , of of of , of of of Power , of of Root , of of of of , of of , and , Extracts of of , of of , Capsules of Root of Redglisse of Natrol, Arthro - Rx, Redglisse of Response Nature Capsules Phytosome Redglisse Grasses Nature, Redglisse Grasses Nature Capsules Power To Be able Certified, Root Redglisse Solaray, Tea The redglisse Blocks and Chews, Soother of Stomach
Common forms
Capsules: 100 to 520 roots of redglisse of mg
The liquid extracts: the extract of redglisse, the extract of redglisse of deglycyrrhizinized
Tablets: 7 mg of root of redglisse and 333 mg of pure concentrated garlic
So available in the candy, chewing eraser, the herbal tea, the throat lozenges, and the tobacco products.
Source
Most of the medicinal products use the roots and the dried rhizomes of Glycyrrhiza Zabra, a constant grass or a small tree of growing low level. The Spanish redglisse, the variety the more town, is diverted from G. glabra var. typica. The plants of redglisse are natal to the Mediterranean but widely cultivated to the United States, Russia, Spain, Turkey, Greece, India, Italy, Iran, and Iraq.
Chemical components
The rhizomes and the roots contain 5% to 9% glycyrrhizin (the acid of glycyrrhizic), a glycoside that is 50 more soft time than Sugar. Hydrolyzes it acid of glycyrrhetic of yields of glycyrrhizin, that is not soft. The others composed include ammonia, oleane triterpenoids, the glucose, mannose, and the sucrose. The aqueous extracts of redglisse contain 10% to 20% glycyrrhizin.
Actions
Glycyrrhizin is hydrolised by the intestinal flora to the form pharmacologiquement activates, the acid of glycyrrhetic. The principal oflicorice of effect is at potentiate, instead of imitating, the endogenous steroids.
The studies in the animals suggest that the acid of glycyrrhizin and glycyrrhetic have effects anti-arsonists soft. Glycyrrhizin can stimulate the synthesis muqueuse gastric by the effects on prostaglandins, that can explain its property of ulcer cure.
Incidentally, the redglisse has effective softening (calm) and the property expectorating and the soft laxative and the antispasmodic effects. A Chinese preparation of redglisse called Zhigancao was found to have the effects of antiarrhythmic, including extended RP and the intervals of QT. Glycyrrhizin can lower also levels of cholesterol and triglycedride and exercises antianemic, antihepatotoxic, and the effects immunodedpressifs.
Retrieved usages
Because of his anecdotic usage for the gastric irritation, the drifts of redglisse were studied for the action of antipeptic. The redglisse also was evaluated as a treatment for the disease of Addison and was found to improve the activity of mineralocorticoid but could not imitate it when the activity surrednale was leaves.
The acid of Glycyrrhizic was used as a shampooing to reduce the secretion of sebum of hairy leather and for the cold wounds, the eczema, and the mouth ulcers.
To the United States, glycyrrhizin principally is used as a perfume and sweeten agent for the bitter drugs, and in the drinks, the candies, chewing eraser, the tobacco products, and toothpaste. It also is added to some cough and to the cold preparations for his expectorant and to the softening effects.
Dosage
For the ulcer liqueur, 200 to 600 mg P.O. of glycyrrhizin daily for not longer than 6 weeks, according to the E of German Commission.
Following tea is believed to furnish glycyrrhizin in the middle of this dosage range: 1 small spoon (2 to 4 g) of crude redglisse to the cup of Yo (120 ml) to boil water, simmered for 5 minutes. Cool, tension, and take P.O. t. I. d. after the food.
Unfavorable reactions
CNS: the very tense encephalopathy.
THE curriculum vitae: the failure of heart and the cardiac taken one (with the overdose), the tachycardia ventriculaire.
EENT: the loss and the visual disturbances passengers after the ingestion of 1,4 to 2 candies of oflicorice of book.
Endocrine: the growth delay reduced levels of testosterone of sedrum.
GU: the damages tubulaires kidney.
Metabolism: hypokalemia pseudoprimary hyperaldosteronism.
Squeletto-musculaire: muscle weakness (with hypokalemia), myopathies, rhabdomyolysis.
Respiratory: the lung edema.
Interactions
Antihypertensives, the diuretics: Can increase the effects of hypokalemic of some diuretics. Eviter the administration with the redglisse.
The corticoa¯des (including current) : Can increase effects. Use together cautiously.
Digoxin: Can induce hypokalemia; the risk of poisonousness of digital one. Eviter the administration with the redglisse.
Loratadine, procainamide, quinidine, the other drugs that can extend the interval of QT: Can have effects additives. Use together cautiously.
Spironolactone: Can block the ulca¨re-guedrison and the effects aldosterone-affectiant of redglisse. Eviter the administration with the redglisse.
Counterindications and precautions
The redglisse is contraindicated in the patients with the arrhythmias; curriculum vitae, the kidney or hepatic disease; or the hypertension. Eviter the usage it in pregnant or the seinÂnourrissant of the patients; the effects are unknown. Use cautiously under the medical check in the elderly patients.
Special considerations
Check for hypokalemia in the diuretics of reception of patient.
A big only dose of redglisse is less probable to cause poisonousness that the taken one extended smaller quantities.
Poison vigilant Redglisse can be insidious. The supervisor for pseudoprimary hyperaldosteronism causing effect mineralocorticoid-affectiant (the headache, the lethargy, the retention of sodium and water, hypokalemia, the hypertension, and heart failure). Check for the edlectrolyte (the potassium, calcium, and sodium) the imbalances, alkalosis, the abnormalities of electrocardiographic, and the hypertension.
Warn the danger patient of take of excessive and chronic redglisse, including the fluid retention and the imbalances of edlectrolyte.
Inform the patient of interactions of potential drug.
The points of Interest
The redglisse was used since Roman meddicinalment stopwatch and is popular in the medicine to bases Chinese plants.
More "the candy of redglisse" sold to the United States is perfumed with the oil of anise and does not contain in fact of the redglisse.
Commentary
Although the drifts of redglisse were studied for the usage against the disease of ulcer liqueur, such products did not execute better than O'CLOCK 2 opposing ones and well less could be tolerated. The acid of Glycyrrhetic can the role of playa in to increase the current action of steroids of low power while to minimize the system effects, but this research always is preliminary. The acid of Glycyrrhetic is the principal cause of syndrome of pseudohyperaldosteronism of redglisse-induit seen with the ingestion of redglisse, because of his inhibiting effect on the enzyme 11 silly hydroxysteroid dehydrogenase. Etonnamment, the redglisse in any form, even as the candy, cautiously should be considered because the chronic ingestion of low doses just like of high doses can be toxic, illustrated by an event unfavorable serious multitude informed in the literature.
